2025 NFL Season Kickoff: Super Bowl Favorites, Week 1 Matchups, and Expert Analysis

As the 2025 NFL season approaches, now is the opportune moment to evaluate the frontrunners for the Super Bowl. The defending champions, Philadelphia Eagles, enter as bookmakers’ top pick to secure another title. However, the challenge of back-to-back victories is daunting, with numerous teams poised to dethrone them.For those looking to place bets, Fanatics Sportsbook offers exciting odds, including the Eagles at +650, followed closely by the Buffalo Bills and Baltimore Ravens at +700, among others.In terms of Week 1 matchups, exciting games are set to unfold between powerhouses like the Eagles and Cowboys, as well as the Bills against Ravens. As we preview the season, the Bills stand out as a compelling choice given their recent playoff misfortunes. With MVP Josh Allen at the helm, coupled with strategic draft picks, they aim for a breakthrough. Watch for potential challengers like the Lions, who aim to secure their first Super Bowl appearance this season.