Still No Evidence COVID-19 Vaccination Increases Cancer Risk, Despite Posts

SciCheck Digest It has not been shown that COVID-19 vaccines cause or accelerate cancer. Yet opponents of the vaccines say a new review article “has found that COVID-19 mRNA vaccines could aid cancer development.” The review conclusions are mainly based on the misinterpretation of a study on mRNA cancer vaccines in mice. How is mRNA in vaccines delivered to cells? How is mRNA in vaccines delivered to cells? Messenger RNA, or mRNA, vaccines work by instructing a small number of a person’s cells to make specific proteins. In the case of the approved mRNA vaccines for COVID-19, the cells make spike protein — one component of the virus that causes COVID-19. For mRNA vaccines to work, it’s not enough to just put mRNA molecules into a vial and then inject them into a person’s muscle. One innovation that made the current mRNA vaccines possible was the use of lipids to encircle the mRNA molecules. These fatty structures — called lipid nanoparticles — protect the mRNA from being broken down prematurely. They also help the mRNA cross the cell membrane and get into cells. The approved mRNA vaccines for COVID-19 each use a blend of four types of lipids. Once the...